Equipment and services for preparative SFC


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Coming in October

SPICA 2014


SPICA will be held this year in the Congress Center, Basel, Switzerland on October 5 - 8. PIC Solution will be there! Visit PIC Solution at our booth and look out for our lecture on X-Injection.

SFC 2014


PIC Solution will attend. Visit our booth and look for our posters.


July 2014

PREP 2014.

PIC Solution presented a paper: "Extraction-Injection as a solution to the demands of sample introduction in preparative SFC".

Contact PIC Solution for a copy of the presentation.


January 2014

Supercritical Fluid Extraction

Supercritical Fluid Extraction systems are now available from PIC Solution. These systems are built upon the proven SFC instruments, bringing reliability and reproducibility to supercritical fluid extractions from multi-extractor method development units to dedicated large-scale extraction systems.


August 2013


An alternative injection technique (X-Injection) is now available. This involves dissolving the sample in the supercritical fluid mobile phase, thus avoiding the problems of band distortion or broadening associated with conventional injection techniques as well as that of the sample precipitating in the column on mixing with the mobile phase. For more information, look at our application note (see below) on extraction-injection.


July 2013

MS detection is now available.

We are pleased to announce that an option for MS detection is now available for both analytical and preparative systems.


June 2013

CO2 recycle available on all PIC Solution SFC systems

prep 100 greenA new module is available which allows CO2 recycle on the smaller SFC units - the PREP 200 and above have CO2 recycle built-in. The module does not change the system footprint but gives the same high recovery values as in the larger SFC systems.





PIC News

The PIC Solution newsletter - PIC News - which highlights PIC Solution products and activities is available. If you are not receiving it, please use the "send us a message" option in the Contacts window (or click here) to be put on the mailing list.


Application Notes

Application notes are now available which describe aspects of the operation of PICLab SFC systems.

1-13. Reproducibility of the SFC-PICLab Hybrid 10-100 system in analytical mode

2-13. Using threshold-only collection

3-13. Preparative reproducibility of the SFC-PICLab Hybrid system

4-13. MS Detection

5-13. Extraction-injection

6-13. Mixed vs Modifier stream injection


Conferences 2014

Readers may be interested in the following conferences:

SPICA 2014

will be held at the Congress Centre, Basel, Switzerland, 5 to 8 October.

SFC 2014 - 8th International Conference on Packed Column SFC

will be held at the Congress Centre, Basel, Switzerland, 8 to 10 October.

PIC Solution is a global supplier of equipment and services for supercritical fluid chromatography (SFC). With more than 18 years of experience and expertise in preparative SFC equipment design and applications, PIC-Solution can provide the best customized solution for your separation laboratory where the goal is to obtain highly pure molecules rapidly and effectively.

Founded by chromatographers experienced in preparative separations, PIC-Solution offers systems for analytical SFC, preparative SFC and preparative HPLC as well as the innovative SFC-PICLab Hybrid™ system which combines an analytical SFC and a preparative SFC system in a single unit. Very recently, PIC Solution has added a range of supercritical fluid extraction systems to its product line-up.

In addition to equipment, PIC Solution provides preparative SFC, HPLC and Simulated Moving Bed (SMB) chromatography columns as well as semi-preparative SFC column hardware. The preparative columns use dynamic axial compression technology and can be used in this mode with the FlexPacker™ unit or can be used as stand-alone columns by virtue of the innovative piston locking system developed by PIC-Solution.

Click here to send a message to PIC Solution

PIC Solution Inc.

P O Box 191
Media, PA 19065
Tel: (484) 319 4281
Fax: (484) 639 0118


PIC Solution SAS

Agroparc - Creativa - Bat B,
200 rue Michel de Montaigne, BP 31222
84911 Avignon Cedex 09
Tel: + 33 (0)4 32 70 19 79
Fax: +33 (0)4 32 70 02 67